10/22/00 – Las Vegas, Nevada is a two-disc live album and the sixty-second in a series of 72 live bootlegs released by the American alternative rock band Pearl Jam from the band's 2000 Binaural Tour. It was released along with the other official bootlegs from the second North American leg of the tour on March 27, 2001.

The Pearl Jam "official" bootlegs are a large, continually growing series of live albums by the American alternative rock band Pearl Jam. Pearl Jam noted the desire of fans to own a copy of the shows they attended and the popularity of bootleg recordings. They had been open in the past about allowing fans to make amateur recordings, and these "official bootlegs" were an attempt to provide a more affordable and better quality product. The official bootlegs are a complete record of almost every show the band plays, excluding club "warm-up" dates."The Official Bootlegs series is them working outside the system… That's revolutionary. They're geniuses, I'm telling you… I've spent way too much money on Official Bootlegs, but the [2010] Hyde Park show when we supported them is my favourite, mainly because Eddie [Vedder, singer] dedicates 'State of Love and Trust' to me… Pearl Jam are good enough to justify that many bootlegs. They vary their set pretty extremely from night to night… You get different versions of songs, compare them, see how a tour went. Maybe it started off a little rough and it got awesome in the end." – Brian Fallon, singer, The Gaslight Anthem