100 Eleventh Avenue is a 23-story residential tower at the intersection of 19th Street and Eleventh Avenue in the borough of Manhattan, New York City, New York. The building is described as "a vision machine" by the architect Jean Nouvel. It has one of the most technologically advanced curtain wall systems in New York City, but also refers to West Chelsea masonry industrial architectural traditions.

Eleventh Avenue is a north–south thoroughfare on the far West Side of the borough of Manhattan in New York City, located near the Hudson River. Eleventh Avenue originates in the Meatpacking District in the Greenwich Village and West Village neighborhoods at Gansevoort Street, where Eleventh Avenue, Tenth Avenue, and West Street intersect. It is considered part of the West Side Highway between 22nd and Gansevoort Streets.