100 Mile House is a district municipality located in the South Cariboo region of central British Columbia, Canada.

The Cariboo Gold Rush was a gold rush in the Colony of British Columbia, which later became the Canadian province of British Columbia. The first gold discovery was made at Hills Bar in 1858, followed by more strikes in 1859 on the Horsefly River, and on Keithley Creek and Antler Creek in 1860. The actual rush did not begin until 1861, when these discoveries were widely publicized. By 1865, following the strikes along Williams Creek, the rush was in full swing.