10 Lafayette Square, also known as the Tishman Building, is a high-rise office tower located in Lafayette Square in Buffalo, New York. Completed in 1959, it is the thirteenth-tallest building in Buffalo, standing at 263 feet and 20 stories tall. The building is located adjacent to the Rand Building and built in the International Style. The structural frames for the building are not steel, but concrete beams and columns. The building architects were Emery Roth & Sons of New York City.

Lafayette Square is a park in the center of downtown Buffalo, Erie County, New York, United States, that hosts a Civil War monument. The block, which was once square, is lined by many of the city's tallest buildings. The square was named for General Lafayette, who visited Buffalo in 1825.