The 10th Marine Regiment is an artillery regiment of the United States Marine Corps based at Marine Corps Base Camp Lejeune, North Carolina. They fall under the command of the 2nd Marine Division and the II Marine Expeditionary Force.

Marine Corps Base Camp Lejeune is a 246-square-mile (640-square-kilometer) United States military training facility in Jacksonville, North Carolina. Its 14 miles of beaches make the base a major area for amphibious assault training, and its location between two deep-water ports allows for fast deployments. The main base is supplemented by six satellite facilities: Marine Corps Air Station New River, Camp Geiger, Stone Bay, Courthouse Bay, Camp Johnson, and the Greater Sandy Run Training Area. The Marine Corps port facility is in Beaufort, at the southern tip of Radio Island. It is occupied only during military port operations.