The 110th Cavalry is an inactive parent cavalry regiment of the United States Army National Guard. Constituted as the 26th Cavalry under the Combat Arms Regimental System in 1963, its 1st Squadron served with the 26th Infantry Division during the Cold War. It was renumbered in 1988 as the 110th and reorganized under the United States Army Regimental System in 1988 before the 1st Squadron inactivated in 1996 as a result of reductions in the National Guard after the end of the Cold War.

The Massachusetts National Guard is the National Guard component for the Commonwealth of Massachusetts. Founded as the Massachusetts Bay Colonial Militia on December 13, 1636, it contains the oldest units in the United States Army. What is today's Massachusetts National Guard evolved through many different forms. Originally founded as a defensive militia for Puritan colonists in the Massachusetts Bay Colony, the militia evolved into a highly organized and armed fighting force. The Massachusetts militia served as a central organ of the New England revolutionary fighting force during the early American Revolution and a major component in the Continental Army under George Washington.