The 1294 papal conclave was convoked in Naples after the resignation of Pope Celestine V on 13 December 1294. Celestine V had only months earlier restored the election procedures set forth in the papal bull Ubi periculum of Pope Gregory X, which had been suspended by Pope Adrian V in July 1276. Every papal election since then has been a papal conclave. It was the first papal conclave held during the lifetime of the preceding pontiff, an event not repeated until the 2013 papal conclave following the resignation of Pope Benedict XVI.

The 1292–94 papal election, was the last papal election which did not take the form of a papal conclave. After the death of Pope Nicholas IV on 4 April 1292, the eleven surviving cardinals deliberated for more than two years before electing the third of six non-cardinals to be elected pope during the Late Middle Ages: Pietro da Morrone, who took the name Pope Celestine V.