12 Discípulos is the debut compilation album, and fifth overall, by Puerto Rican reggaeton rapper Eddie Dee. It was released on January 29, 2004, and independently distributed by Diamond Music. 12 Discípulos features eleven other reggaeton musicians, who were among the most requested in the genre at the time. These include Daddy Yankee, along with Ivy Queen, Tego Calderón, Voltio, Vico C, Zion & Lennox, Nicky Jam, Johnny Prez, Gallego, and Wiso G.

Tegui Calderón Rosario is a Puerto Rican rapper, singer and actor. He began his musical career in 1996 and was supported by the famous Puerto Rican rapper Eddie Dee, who invited him on his second studio album, El Terrorista de la Lírica, released in 2000. Calderón reached international success in 2003 with his first album, El Abayarde, which sold 300,000 copies worldwide and was nominated for a Latin Grammy Award. His importance in reggaeton music led him to participate in Eddie Dee's 12 Discípulos album in 2004. He released three more studio albums between 2006 and 2015, varying in styles, focusing more in hip hop and African music rather than reggaeton in The Underdog/El Subestimado (2006) and El Abayarde Contraataca (2007). His fourth studio album, El Que Sabe, Sabe, released in 2015, won a Latin Grammy Award for Best Urban Music Album. In the same year, he announced that he is planning a studio album alongside the Puerto Rican singer Yandel titled El Blanco y el Negro.