The 12th Special Operations Squadron is assigned to the 27th Special Operations Group at Cannon Air Force Base, New Mexico. Its mission is the launch and recovery of MQ-9 Reaper Remotely Piloted Aircraft from unprepared locations throughout the world. The squadron was activated in 2015 to replace a detachment that had been performing the same mission since October 2013.

Cannon Air Force Base is a United States Air Force base, located approximately 7 miles (11 km) southwest of Clovis, New Mexico. The host unit at Cannon is the 27th Special Operations Wing also known as "The Steadfast Line". It is under the jurisdiction of Air Force Special Operations Command (AFSOC) which activated at the base on 1 October 2007. The 27 SOW plans and executes specialized and contingency operations using advanced aircraft, tactics and air refueling techniques to infiltrate, exfiltrate and resupply special operations forces (SOF) and provide intelligence, surveillance and reconnaissance and close air support in support of SOF operations.