The 1669 eruption of Mount Etna is the largest-recorded historical eruption of the volcano on the east coast of Sicily, Italy. After several weeks of increasing seismic activity that damaged the town of Nicolosi and other settlements, an eruption fissure opened on the southeastern flank of Etna during the night of 10–11 March. Several more fissures became active during 11 March, erupting pyroclastics and tephra that fell over Sicily and accumulated to form the Monti Rossi scoria cone.

The 1693 Sicily earthquake struck parts of southern Italy near Sicily, Calabria, and Malta on 11 January at around 21:00 local time. This earthquake was preceded by a damaging foreshock on 9 January. The main quake had an estimated magnitude of 7.4 on the moment magnitude scale, the most powerful in Italian recorded history, and a maximum intensity of XI (Extreme) on the Mercalli intensity scale, destroying at least 70 towns and cities, seriously affecting an area of 5,600 square kilometres (2,200 sq mi) and causing the death of about 60,000 people.