16th Street station is a former Southern Pacific Railroad station in the Prescott neighborhood of Oakland, California, United States. The Beaux-Arts building was designed by architect Jarvis Hunt, a preeminent railroad station architect, and opened in 1912. The station has not been served by trains since 1994.

Prescott is a residential neighborhood and commercial district in West Oakland in Oakland, California. The neighborhood boundaries are Mandela Parkway to the east, 7th Street to the south, West Grand Avenue to the north, and Frontage Road to the west.