The Hokitika by-election 1878 was a by-election held in the multi-member Hokitika electorate during the 6th New Zealand Parliament, on 26 June 1878. The by-election was caused by the resignation of incumbent MP Charles Button and was won by Seymour Thorne George, who defeated Gerard George Fitzgerald. Thorne George was suggested as a candidate by the premier, Sir George Grey; he was the Premier's nephew, and lived in the North Island.

Charles Edward Button was a solicitor, Supreme Court judge, Mayor of Hokitika and later Birkenhead, and an independent conservative Member of Parliament in New Zealand. Born in Tasmania, he came to New Zealand with his wife in 1863. He first lived in Invercargill, then in Westland, and after a brief period in Christchurch, he settled in Auckland. He was an MP for two periods, and when he was first elected to Parliament, he beat his colleague, friend, political opponent, and later Premier Richard Seddon; this was the only election defeat ever suffered by Seddon.