The 1887–88 Scottish Cup was the 15th season of Scotland's most prestigious football knockout competition. Renton won the competition for the second time after they beat Cambuslang 6–1 in the final. The result set a new record as the largest margin of victory in a Scottish Cup Final - a record that was equalled by Celtic in 1972 but has never been bettered.

Renton Football Club was a football club based in Renton, West Dunbartonshire, Scotland. Formed in 1872, it was a prominent team in the early history of Scottish football, and was one of the teams that featured in the first ever Scottish Cup fixture. It won the competition twice, in 1885 and 1888, and was also runners-up three times. Its 6–1 win against Cambuslang in 1888 is the joint record win in a Scottish Cup final.