18 East 50th Street, also known as the Hampton Shops Building and the New York Health & Racquet Club Building, is an office building in the Midtown Manhattan neighborhood of New York City. Located on the south side of 50th Street, on the middle of the block between Fifth Avenue and Madison Avenue, it was designed by William Lawrence Rouse, Lafayette Anthony Goldstone, and Joseph L. Steinam.

St. Patrick's Cathedral is a Catholic cathedral in the Midtown Manhattan neighborhood of New York City. It is the seat of the Archbishop of New York as well as a parish church. The cathedral occupies a city block bounded by Fifth Avenue, Madison Avenue, 50th Street, and 51st Street, directly across from Rockefeller Center. Designed by James Renwick Jr., it is the largest Gothic Revival Catholic cathedral in North America.