18 Wheeler: American Pro Trucker, known in Japan as 18 Wheeler , is an arcade game developed by Sega AM2 and distributed by Sega. The game was released in arcades in 2000 and ported to the Dreamcast in 2001. It was released for the PlayStation 2 in 2001 and GameCube in 2002 by Acclaim Entertainment. Sega followed up on the success of 18 Wheeler with a sequel, The King of Route 66, which was released in the arcades in 2002 and ported to the PlayStation 2. This was one of the final arcade games to be ported to the Dreamcast after its discontinuation, before Sega became a third-party developer.

Sega AM Research & Development No. 2, previously known as SEGA-AM2 Co., Ltd., is a video game development team within the Japanese multinational video game developer Sega. Yu Suzuki, who had previously developed arcade games for Sega including Hang-On and Out Run, was the first manager of the department.