The 18th Georgia Infantry Regiment was an infantry regiment in the Confederate Army during the American Civil War. Originally brigaded with the three Texas regiments of John Bell Hood's Texas Brigade, it was transferred to Thomas R.R. Cobb's Georgia Brigade after the Battle of Antietam in late 1862. After General Cobb was mortally wounded at the Battle of Fredericksburg, the original colonel of the 18th Georgia, William T. Wofford, became Brigadier General of the Georgia Brigade.

The Texas Brigade was an infantry formation of the Confederate Army that distinguished itself in the American Civil War. Along with the Stonewall Brigade, they were considered the Confederate Army's shock troops. It fought in every major battle of the Eastern Theater except Chancellorsville.