The 1901 Purdue Boilermakers football team was an American football team that represented Purdue University during the 1901 Western Conference football season. The Boilermakers compiled a 4–4–1 record and outscored their opponents by a total of 138 to 66 in their fourth, non-consecutive season under head coach D. M. Balliet. John F. G. Miller was the team captain.

The 1901 Western Conference football season was the sixth season of college football played by the member schools of the Western Conference and was a part of the 1901 college football season.