The 1903 Clemson Tigers football team represented Clemson Agricultural College—now known as Clemson University—as a member of the Southern Intercollegiate Athletic Association (SIAA) during the 1903 college football season. Led by John Heisman in his fourth and final season as head coach, the Tigers compiled an overall record of 4–1–1 with mark of 2–0–1 in SIAA play.

John William Heisman was a player and coach of American football, baseball, and basketball, as well as a sportswriter and actor. He served as the head football coach at Oberlin College, Buchtel College, Auburn University, Clemson University, Georgia Tech, the University of Pennsylvania, Washington & Jefferson College, and Rice University, compiling a career college football record of 186–70–18.