The 1910 Massachusetts gubernatorial election was held on November 8, 1910. Incumbent Republican Governor Eben S. Draper was defeated for re-election to a third term by former Republican Eugene Foss, running as a Democrat.

Eben Sumner Draper was an American businessman and politician from Massachusetts. He was for many years a leading figure in what later became the Draper Corporation, the dominant manufacturer of cotton textile process machinery in the world during the late 19th and early 20th centuries. He served as the 44th governor of Massachusetts from 1909 to 1911.