The 1914 United States Senate election in Colorado took place on November 3, 1914. It was the first direct U.S. Senate election in Colorado following the ratification of the Seventeenth Amendment. Incumbent U.S. Senator Charles S. Thomas, a Democrat, who was first elected by the state legislature to fill a vacancy in 1913, ran for re-election to a full term.

Charles Spalding Thomas was a Confederate soldier and later United States senator from Colorado. Born in Darien, Georgia, he attended private schools in Georgia and Connecticut, and served briefly in the Confederate Army.