The 1922 Dixie Classic was a post-season college football bowl game between the Texas A&M Aggies and the Centre College Praying Colonels on January 2, 1922, at Fair Park Stadium in Dallas, Texas. Texas A&M defeated Centre 22–14. It is also the game in which Texas A&M's 12th man tradition originated.

The Centre Colonels football team, historically also known as the Praying Colonels, represents Centre College in NCAA Division III competition. The Colonels currently play in the Southern Athletic Association (SAA), which was established in 2011. Before the establishment of the SAA, Centre played 50 seasons in the Southern Collegiate Athletic Conference (SCAC). Despite the school's small size, the football team has historically had success and possesses a strong tradition. At the end of the 2008 season, the school ranked as the 12th winningest school in Division III with an all-time record of 509–374–37.