The 1926 United States Senate elections were elections for the United States Senate that occurred in the middle of Republican President Calvin Coolidge's second term. The 32 seats of Class 3 were contested in regular elections, and special elections were held to fill vacancies. The Republican majority was reduced by seven seats.

Charles Curtis was an American attorney and Republican politician from Kansas who served as the 31st vice president of the United States from 1929 to 1933 under Herbert Hoover. He had served as the Senate Majority Leader from 1924 to 1929. A member of the Kaw Nation born in the Kansas Territory, Curtis was the first Native American and first person in a racial minority group to reach either of the highest offices in the federal executive branch.