During the 1948–49 English football season, Brentford competed in the Football League Second Division. It was Harry Curtis' final season as manager and he was replaced by Jackie Gibbons in February 1949. Brentford ended the season in 18th-place, just one point away from a second relegation in three seasons, though the Bees advanced to the sixth round of the FA Cup for the third time in the club's history.

Thomas Ronald Manley was an English professional footballer who made over 300 appearances in the Football League for Manchester United and Brentford as a utility player. He later managed hometown club Northwich Victoria in non-League football.