The 1951 Pro Bowl was the National Football League's inaugural Pro Bowl which featured the league's outstanding performers from the 1950 season. The game was played on Sunday, January 14, 1951, at the Los Angeles Memorial Coliseum in Los Angeles, California in front of 53,676 fans. The American Conference squad defeated the National Conference by a score of 28–27. The player were selected by a vote of each conferences coaches along with the sports editors of the newspapers in the Los Angeles area, where the game was contested.

The National Football League All-Star Game (1939–1942), Pro Bowl (1951–2022), or Pro Bowl Games is an annual event held by the National Football League (NFL) featuring the league's star players.