The 1952 United States Senate election in Indiana took place on November 4, 1952. Incumbent Republican U.S. Senator William E. Jenner was re-elected to a second term in office over Governor of Indiana

William Ezra Jenner was an American lawyer and politician from the state of Indiana. A Republican, Jenner was an Indiana state senator from 1934 to 1942, and a U.S. senator from 1944 to 1945 and again