The 1958 Grand Prix motorcycle racing season was the tenth F.I.M. Road Racing World Championship Grand Prix season. The season consisted of seven Grand Prix races in five classes: 500cc, 350cc, 250cc, 125cc and Sidecars 500cc. It began on 6 June, with Isle of Man TT and ended with Nations Grand Prix in Italy on 14 September.

MV Agusta is a high end motorcycle manufacturer founded by Count Domenico Agusta on 19 January 1945 as one of the branches of the Agusta aircraft company near Milan in Cascina Costa, Italy. The abbreviation MV stands for Meccanica (mechanics) Verghera, the hamlet where the first MVs were made. The modern headquarters and main production facilities are located in Varese, Italy on the shore of Lake Varese.