General elections were held in Nepal from 18 February to 3 April 1959 to elect the 109 members of the first House of Representatives, the lower house of the Parliament of Nepal. They were held under the provisions of the 1959 constitution, which had been adopted on 12 February. More than 4.25 million people out of an overall population of about 8.55 million (1954) were eligible to vote. Voter turnout was 42.18%.

The House of Representatives, or Pratinidhi Sabha, is one of the houses of the Federal Parliament of Nepal, with the other house being the National Assembly. Members of the House of Representatives are elected through a parallel voting system. They hold their seats for five years or until the body is dissolved by the President on the advice of the council of ministers. The house meets at the International Convention Centre in Kathmandu.