General elections were held in British Guiana on 7 December 1964. They saw the People's Progressive Party win 24 of the 53 seats. However, the People's National Congress and United Force were able to form a coalition government with a working majority. Despite losing the elections, Prime Minister and PPP leader Cheddi Jagan refused to resign, and had to be removed by Governor Richard Luyt, with Forbes Burnham replacing him. Voter turnout was 97.0%.

The People's Progressive Party/Civic (PPP/C) is a major political party in Guyana. As of 2020, the party holds 33 of the 65 seats in the National Assembly and forms the government. It has been the ruling party in the past as well, most recently between 1992 and 2015. In Guyana's ethnically divided political landscape, the PPP/C is a multi-ethnic organization that is supported primarily by Indo-Guyanese people.