The 1964 Republican National Convention took place in the Cow Palace, Daly City, California, from July 13 to July 16, 1964. Before 1964, there had been only one national Republican convention on the West Coast, the 1956 Republican National Convention, which also took place in the Cow Palace. Many believed that a convention at San Francisco indicated the rising power of the Republican Party in the west.

The Cow Palace is an indoor arena located in Daly City, California, situated on the city's northern border with neighboring San Francisco. Because the border passes through the property, a portion of the upper parking lot is in San Francisco.