The 1968 Republican National Convention was held at the Miami Beach Convention Center in Miami Beach, Dade County, Florida, USA, from August 5 to August 8, 1968, to select the party's nominee in the general election. It nominated former Vice President Richard M. Nixon for president and Maryland Governor Spiro T. Agnew for vice president. It was the fourth time Nixon had been nominated on the Republican ticket as either its vice presidential or presidential candidate (1960). Symbolic of the South's changing political affiliation, this was the first Republican National Convention held in a prior Confederate State.

The Miami Beach Convention Center is a convention center located in Miami Beach, Florida. Originally opened in 1958, the venue was renovated from 2015 to 2018 for $620 million. The re-imagined and enhanced MBCC includes a 60,000-square-foot Grand Ballroom, four junior ballrooms, 500,000 square feet of flexible exhibition space, 84 meeting rooms, and pre-function space, as well as outdoor spaces and terraces.