The 1972 Major League Baseball season was the first to have games cancelled by a player strike. It was also the last season in which American League pitchers would hit for themselves on a regular basis; the designated hitter rule would go into effect the following season.

The American League East is one of Major League Baseball's six divisions. MLB consists of an East, Central, and West division for each of its two 15-team leagues, the American League (AL) and National League (NL). This division was created before the start of the 1969 season along with the American League West division. Before that time, each league consisted of 10 teams without any divisions.