The 1987 Indianapolis Colts season was the 35th season for the team in the National Football League (NFL) and fourth in Indianapolis. It was also their first full season under head coach Ron Meyer, who had taken over an 0-13 Colts team the previous season after Rod Dowhower was fired.

The 1987 NFL season was the 68th regular season of the National Football League (NFL). This season featured games predominantly played by replacement players, as the National Football League Players Association (NFLPA) players were on strike from weeks four to six with week three being cancelled in its entirety. This remains the last NFL season in which regular-season games were impacted by a labor conflict.