The 1988 Copa Interamericana was the 11th staging of this competition. The final took place between Nacional and Olimpia and was staged over two legs on 5 and 29 March 1989.

The Estadio Nacional Chelato Uclés is a multi-purpose stadium in Tegucigalpa, Honduras. It is used mostly for association football matches. The stadium has a capacity of 35,000 and is the home of football clubs Motagua and Olimpia. This is one of the oldest stadiums in Honduras and has an important historical role for it, since emblematic matches in the history of Honduran Football have been held in this stadium, as well as concerts and presidential inaugurations.