The 1991 NCAA Division I women's basketball tournament began on March 13 and ended on March 31. The tournament featured 48 teams. The Final Four event was hosted by the University of New Orleans, and held at the Lakefront Arena in New Orleans. The Final Four teams consisted of Tennessee, Stanford, Connecticut, and Virginia, with Tennessee defeating Virginia 70-67 (OT) to win its third NCAA title. Virginia's Dawn Staley was named the Most Outstanding Player of the tournament.

The Senator Nat G. Kiefer University of New Orleans Lakefront Arena is an 8,933-seat multi-purpose arena located in New Orleans, Louisiana. The arena is home to the University of New Orleans Privateers men's and women's basketball teams.