The 2001 MBNA Cal Ripken Jr. 400 was a NASCAR Winston Cup Series stock car race held on September 23, 2001, at Dover Downs International Speedway. The race was the 27th of the 2001 NASCAR Winston Cup Series season. The race is notable for being the first NASCAR Cup Series race run after the September 11 attacks.

Dover Motor Speedway is a race track in Dover, Delaware. The track has hosted at least one NASCAR Cup Series race each year since 1969, including two per year from 1971 to 2020. In addition to NASCAR, the track also hosted USAC and the Indy Racing League. The track features one layout, a 1.03 mi (1.66 km) concrete oval, with 24° banking in the turns and 9° banking on the straights. The speedway is owned and operated by Speedway Motorsports.