The 2005-06 Segunda División season was the 75th since its establishment. The first matches were played on August 27, 2005 and the season ended at June 18, 2006.

Real Club Recreativo de Huelva, S.A.D. is a Spanish football club based in Huelva, in the autonomous community of Andalusia. Founded on 23 December 1889, they are the oldest football club in Spain, and currently play in Primera Federación – Group 2, holding home games at Estadio Nuevo Colombino, which has a 21,670 capacity.