The 2005 Canadian Professional Soccer League season was the 8th season for the Canadian Professional Soccer League. The season began on May 21, 2005 and concluded on October 10, 2005 with Oakville Blue Devils defeating Vaughan Shooters 2-1 to win their first CPSL Championship. The final was played at Esther Shiner Stadium, which gave North York Astros a playoff wildcard match. In the regular season the Vaughan Shooters won their first Eastern Conference title, while Hamilton Thunder secured their third Western Conference title. The league increased in membership with the return of the Laval Dynamites. For the first time in the league's history the CPSL introduced a Women's Canada Cup tournament, which included 6 district all-star teams from the existing men's soccer districts.

The Canadian Soccer League is a semi-professional league for Canadian soccer clubs primarily located in the province of Ontario, and claims the history of the Canadian National Soccer League (CNSL). It is a non-FIFA league previously sanctioned by the Canadian Soccer Association (CSA), but now affiliated with the Soccer Federation of Canada (SFC). As of 2023, it consists of seven teams, all located in Ontario. The season usually runs from May to October, with most games played on the weekend followed by a playoff format to determine the overall champion.