The 2006 Notre Dame Fighting Irish football team represented the University of Notre Dame in the 2006 NCAA Division I FBS football season. The team was coached by Charlie Weis and played its home games at Notre Dame Stadium in South Bend, Indiana. The team completed the season with a record of ten wins and three losses that culminated in a post-season appearance in the 2007 Sugar Bowl and a number 19 ranking in the nation.

Charles Joseph Weis Sr. is a former American football coach. He was the head coach for the Notre Dame Fighting Irish from 2005 to 2009 and the Kansas Jayhawks from 2012 to 2014. He also served as an offensive coordinator in the National Football League (NFL) for the New York Jets, New England Patriots, and Kansas City Chiefs. Weis currently hosts "Airing It Out," along with Bob Papa, on Sirius XM NFL Radio.