The 2006 Campeonato Nacional Clausura Copa Banco del Estado was the 80th Chilean League top flight, in which Colo-Colo won its 25th league title after beating Audax Italiano in the finals.

Manuel Alejandro Neira Díaz is a Chilean former professional footballer who played as a forward for clubs including Colo-Colo, UD Las Palmas, Racing Club and Unión Española, and scored 2 goals in 13 i