The 2006 UEFA Super Cup was the 31st edition of the annual UEFA Super Cup, a UEFA-sponsored football club match that pitted the winners of the UEFA Champions League against the winners of the UEFA Cup. It took place at the Stade Louis II in Monaco, on 25 August 2006, and featured two Spanish clubs: Barcelona, who won the 2005–06 UEFA Champions League, against Sevilla, who took the 2005–06 UEFA Cup title. Sevilla beat Barcelona by 3–0 and added its first UEFA Super Cup trophy to its maiden UEFA Cup.

The UEFA Super Cup is an annual super cup football match organised by UEFA and contested by the winners of the two main European club competitions: the UEFA Champions League and UEFA Europa League. The competition's official name was originally the Super Competition, and later the European Super Cup. It was renamed the UEFA Super Cup in 1995, following a policy of rebranding by UEFA.