The 2007 Trinity vs. Millsaps football game is best known for the memorable play that occurred in the game's last two seconds. On October 27, 2007, the NCAA Division III 19th-ranked Trinity University Tigers threw 15 lateral passes and scored a 61-yard touchdown to win a game against the 24th-ranked Millsaps College Majors as time expired in the game. Media sources called the play the "Mississippi Miracle" or "Lateralpalooza." ESPN and other sources said the play was probably "the longest play in college football history" in terms of how much time the play took to complete. On January 7, 2008, the final play of the game was named the Pontiac Game Changing performance of the year.

Trinity University is a private liberal arts college in San Antonio, Texas. Founded in 1869, its student body consists of about 2,600 undergraduate and 200 graduate students. Trinity offers 49 majors and 61 minors among six degree programs, and has an endowment of $1.725 billion.