The 2008 Giro d'Italia was the 91st running of the Giro d'Italia, one of cycling's Grand Tours. It began in Palermo on 10 May and ended in Milan on 1 June. Twenty-two teams entered the race, which was won by Spaniard Alberto Contador of the Astana cycling team. Second and third respectively were Italians Riccardo Riccò and Marzio Bruseghin.

The Giro d'Italia is an annual multiple-stage bicycle race primarily held in Italy, while also starting in, or passing through, other countries. The first race was organized in 1909 to increase sales of the newspaper La Gazzetta dello Sport, and the race is still run by a subsidiary of that paper's owner. The race has been held annually since its first edition in 1909, except during the two world wars. As the Giro gained prominence and popularity, the race was lengthened, and the peloton expanded from primarily Italian participation to riders from all over the world. The Giro is a UCI World Tour event, which means that the teams that compete in the race are mostly UCI WorldTeams, with some additional teams invited as 'wild cards'.