The 2008 Purdue Boilermakers football team represented Purdue University in the Big Ten Conference during the 2008 NCAA Division I FBS football season. Joe Tiller, in his 12th and final season at Purdue, was the team's head coach. The Boilermakers' home games were played at Ross–Ade Stadium in West Lafayette, Indiana. They posted a 4–8 record, finishing in a ninth place tie in the Big Ten.

The 2008 NCAA Division I FBS football season was the highest level of college football competition in the United States organized by the National Collegiate Athletic Association (NCAA).