The 2008 United States Senate election in Alaska was held on November 4, 2008. Incumbent Republican U.S. Senator and former President pro tempore Ted Stevens ran for re-election for an eighth term in the United States Senate. It was one of the ten Senate races that U.S. Senator John Ensign of Nevada, the chairman of the National Republican Senatorial Committee, predicted as being most competitive. The primaries were held on August 26, 2008. Stevens was challenged by Democratic candidate Mark Begich, the mayor of Anchorage and son of former U.S. Representative Nick Begich.

Theodore Fulton Stevens Sr. was an American politician and lawyer who served as a U.S. Senator from Alaska from 1968 to 2009. He was the longest-serving Republican Senator in history at the time he left office. Stevens was the president pro tempore of the United States Senate in the 108th and 109th Congresses from 2003 to 2007, and was the third U.S. Senator to hold the title of president pro tempore emeritus. He was previously Solicitor of the Interior Department from 1960 to 1961. Stevens has been described as one of the most powerful members of Congress and as the most powerful member of Congress from the Northwestern United States.