The 2008 United States presidential election in Nebraska took place on November 4, 2008, as part of the 2008 United States presidential election. Voters chose five electors to the Electoral College, who voted for president and vice president. However, Nebraska is one of the two states of the U.S. that, instead of giving all of its electors to the winner based on its statewide results, allocates just two electoral votes to the winner of the statewide popular vote. The other three electors vote based on their individual congressional district results.

The 2008 United States presidential election was the 56th quadrennial presidential election, held on November 4, 2008. The Democratic ticket of Barack Obama, the junior senator from Illinois, and Joe Biden, the senior senator from Delaware, defeated the Republican ticket of John McCain, the senior senator from Arizona, and Sarah Palin, the governor of Alaska. Obama became the first African American to be elected to the presidency, as well as being only the third sitting United States senator elected president, joining Warren G. Harding and John F. Kennedy. Meanwhile, this was only the second successful all-senator ticket since the 1960 election and is the only election where both major party nominees were sitting senators. This was the first election since 1952 in which neither the incumbent president nor vice president was on the ballot, as well as the first election since 1928 in which neither ran for the nomination.