The 2010–11 Serie B is the seventy-ninth season since its establishment in 1929, and the first one under the rule of the new Lega Serie B. A total of 22 teams contest the league, 15 of which returned from the 2009–10 season, 4 of which have been promoted from Lega Pro Prima Divisione, and three relegated from Serie A.

Antonio Conte is an Italian professional football manager and former player who was most recently the head coach of Premier League club Tottenham Hotspur.