The 2010–11 Temple Owls men's basketball team represented Temple University in the 2010–11 NCAA Division I men's basketball season. The team played their home games at the Liacouras Center, which has a capacity of 10,206. The Owls were in their 29th season as a member of the Atlantic 10 Conference. In the previous season, Temple Owls gained a record of 29–6 and reached the NCAA tournament. The team returned three starters from the previous season, but leading scorer Ryan Brooks and point guard Luis Guzman left, having graduated. They were replaced by new players Aaron Brown, Anthony Lee, and Jimmy McDonnell and graduate student transfer Dutch Gaitley. In the off-season, other Atlantic 10 coaches predicted that Temple Owls would win the league.

The 2010–11 NCAA Division I men's basketball season began on November 8, 2010, with the preliminary games of the 2010 Coaches vs. Cancer Classic, and ended with the 2011 NCAA Division I men's basketball tournament's championship game on April 4, 2011, at Reliant Stadium in Houston. The tournament's first-round games occurred March 15–16, 2011, in Dayton, followed by second and third rounds on Thursday through Sunday, March 17–20. Regional games were March 24–27, with the Final Four played April 2 and 4.