The 2010 Calder Cup playoffs of the American Hockey League began on April 14, 2010. The sixteen teams that qualified, eight from each conference, played best-of-seven series for division semifinals, finals and conference finals. The conference champions, Hershey Bears and Texas Stars, played a best-of-seven series for the Calder Cup that was won by the Hershey Bears in six games. This was the second consecutive Calder Cup for the Bears and their 11th overall.

The Hamilton Bulldogs were a professional ice hockey team in the American Hockey League. They played in Hamilton, Ontario, at FirstOntario Centre, nicknamed 'The Dog Pound'. They were the AHL affiliate of the NHL's Edmonton Oilers and Montreal Canadiens as two separate franchises over 19 seasons of continuous participation in the AHL. The team won the Calder Cup once in its history, in 2007.