The 2010 Minnesota Senate election was held in the U.S. state of Minnesota on November 2, 2010, to elect members to the Senate of the 87th Minnesota Legislature. A primary election was held in several districts on August 10, 2010.

The Minnesota Senate is the upper house of the Legislature of the U.S. state of Minnesota. At 67 members, half as many as the Minnesota House of Representatives, it is the largest upper house of any U.S. state legislature. Floor sessions are held in the west wing of the State Capitol in Saint Paul. Committee hearings, as well as offices for senators and staff, are located north of the State Capitol in the Minnesota Senate Building. Each member of the Minnesota Senate represents approximately 80,000 constituents.