The 2010 NFL season was the 91st regular season of the National Football League (NFL) and the 45th of the Super Bowl era.

The Super Bowl is the annual league championship game of the National Football League (NFL) of the United States. It has served as the final game of every NFL season since 1966, replacing the NFL Championship Game. Since 2022, the game has been played on the second Sunday in February. Prior Super Bowls were played on Sundays in early to mid-January from 1967 to 1978, late January from 1979 to 2003, and the first Sunday of February from 2004 to 2021. Winning teams are awarded the Vince Lombardi Trophy, named after the eponymous coach who won the first two Super Bowls. Because the NFL restricts use of its "Super Bowl" trademark, it is frequently referred to as the "big game" or other generic terms by non-sponsoring corporations. The day that the game is held, is commonly referred to as "Super Bowl Sunday" or simply "Super Sunday".